Journal: Stroke
Article Title: Altered Functional Connectivity Between Cortical Premotor Areas and the Spinal Cord in Chronic Stroke
doi: 10.1161/STROKEAHA.124.048384
Figure Lengend Snippet: Alterations in corticospinal coupling during force generation for ventral premotor cortex (PMV). Psycho-physiological interaction analysis between ipsilesional PMV ( A ) and the spinal cord and overview of the slices displayed along the z axis. B , Group comparison stroke (S) > control (C), controlled for maximum grip force. C , Patients with stroke: correlation with motor impairment, controlled for maximum grip force, age, side; ( Z maps were thresholded by Z >2.0 [group comparison] and | Z |>2.4 [correlation analysis], cluster significance threshold of P <0.05). Spinal cord activations are overlaid on the PAM50_t2-template, and Montreal Neurological Institute (MNI) coordinates are given. All images are in radiological orientation. The coupling strengths in spinal cluster voxels (MNI coordinates as indicated) were extracted and displayed in B and C . au indicates arbitrary units; NHP, Nine-Hole Peg Test; and UEFM, Fugl Meyer assessment of the upper extremity.
Article Snippet: In this cross-sectional study, patients with chronic stroke and healthy controls underwent corticospinal functional magnetic resonance imaging while performing a simple force generation task at the University Medical Center Hamburg-Eppendorf between September 2021 and June 2023.
Techniques: Comparison, Control